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S-Adenosylmethionine (also known as SAMe) is a molecule found in all cells of the body. SAMe is of special importance in hepatocytes, from where it has the capacity to positively influence the metabolism of the whole organism. SAMe participates in the formation of Glutathione, the most important defense mechanism against oxidative stress, since it helps to detoxify harmful molecules, making them soluble and thus facilitating their excretion. Glutathione protects hepatocytes from cell deterioration and death (apoptosis). When the liver is damaged, the activity of the enzyme SAMe synthetase decreases, so that methionine accumulates and SAMe levels decrease. Due to this decrease, less Glutathione is synthesized, causing a failure in the liver function that can affect the entire metabolism of the body.
Silybin is the most abundant and active component of silymarin, an extract of the milk thistle fruit (Silybum marianum). Silybin neutralizes free radicals, thus protecting the liver cells against oxidative damage. It also inhibits the adhesion of toxins, as well as the production of leukotrienes, which are involved in the inflammatory response. For its part, phosphatidylcholine is the main precursor / metabolite of choline, and the main constituent of lipoproteins in the bloodstream and cell membranes. It is also the main component of bile, and plays a key role in mitochondrial energy transformation and in the elimination of residues from cellular metabolism.
Product for the maintenance of liver function in dogs and cats.
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