Previcox contains the active substance firocoxib, which belongs to a class of medicines having anti-inflammatory effect.
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What is Previcox?
Previcox contains the active substance firocoxib, which belongs to a class of medicines having effect
antiinflammatory. Previcox is presented as chewable tablets for dogs (57 mg and 227 mg) and
It is also authorized as an oral paste for horses (8.2 mg / g).
What is Previcox used for?
Previcox is indicated for the relief of pain and inflammation associated with osteoarthritis in dogs
and to relieve pain and inflammation associated with osteoarthritis and reduction of associated lameness in
The dose, duration and frequency of treatment depend on the weight and species of animal and
and the condition being treated. For more information, see the prospectus.
How does Previcox?
Previcox contains firocoxib, which belongs to the group of drugs called nonsteroidal anti-inflammatory
steroidal (NSAID) group of Coxib, acting by selective inhibition of
cyclooxygenase-2 (COX-2). Coxibs display analgesic, anti-inflammatory properties and
antipyretic. Firocoxib blocks the enzyme (cyclooxygenase) involved in the production of
prostaglandins. As the prostaglandins are substances that trigger pain, exudation and
inflammation, Previcox reduce these reactions.
What kind of studies have been conducted with Previcox?
Previcox has been studied in laboratory animals as well as in dogs and horses that were treated
in various veterinary clinics across Europe ( "clinical studies").
Previcox chewable tablets for dogs were studied in two large European field studies
in dogs for a period of 90 days. The results improved the score on the scale
lameness in dogs with established osteoarthritis. The product was similar to other reference products
(Carprofen and meloxicam, respectively).
Two multicenter studies (one in the United States and one in Europe) were performed to investigate
the efficacy, safety and acceptability of firocoxib under field conditions when administered
equines orally once daily for 14 days at a dose of 0.1 mg / kg. The CVMP concluded that
Previcox oral paste was as effective as other authorized products (phenylbutazone and vedaprofen)
to relieve pain and inflammation associated with osteoarthritis and reduction of associated lameness in
What benefit has Previcox shown during the studies?
Previcox tablets for dogs improved the rating scale of pain relief and
inflammation. Administration of the product according to the recommended dosage regime for a
90 days improved the rating scale of lameness in dogs with osteoarthritis
Previcox oral paste administered once daily for 14 days at a dose of 0.1 mg / kg improved
score scale clinical lameness and soft tissue injuries in horses and helped
also to relieve pain and inflammation associated with osteoarthritis in horses.
What is the risk associated with Previcox?
Previcox side effects are the same as those seen with other drugs
belonging to that class of products (NSAIDs) such as oral lesions (tissue damage) in the mouth of the
horses, soft / diarrhea or lethargy feces. These reactions are usually transient and reversible
when treatment is stopped.
Previcox must not be administered with corticosteroids or other NSAIDs. this medicine
care should be taken when used with molecules acting on the
renal blood flow, such as diuretics.
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