Composition per tablet:
Active ingredient: Firocoxib 62.5 mg.
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Firocoxib is a molecule well known for its good efficacy and safety profile. It is a non-steroidal anti-inflammatory drug (NSAID) belonging to the Coxibs group, which acts by selective inhibition of cyclooxygenase-2 (COX-2).
Cyclooxygenase is an enzyme responsible for the production of prostaglandins and we know that prostaglandins play an important role both in physiological functions and in the development of inflammatory and painful processes.
Why is it important to act selectively? With the use of more selective anti-inflammatory drugs we want to protect the production of prostaglandins that have a physiological function, avoiding the formation of those that intervene as mediators of inflammatory and painful processes.
COX-2 is the isomorph of cyclooxygenase that has been shown to be induced by pro-inflammatory stimuli. The activation of COX-2 has been linked to the synthesis of prostanoids mediating pain, inflammation and fever.
In in vitro tests on canine whole blood, firocoxib is approximately 380 times more selective for COX-2 than for COX-1.
Therefore, Firodyl®, by inhibiting COX-2, shows analgesic, anti-inflammatory and antipyretic properties.
Firodyl® offers four qualities that make a difference:
1. EXCELLENT PALATABILITY
One of the challenges faced by long-term treatments, as in this case, managing osteoarthritis pain, is compliance.
And to achieve good adherence to treatment, it is essential to make it easy for caregivers.
2. FRACTIONABLE TABLETS
SNAP-TABLETS is a technology that allows tablets to be divided into 4 equal parts just by pressing with a finger.
3. AVOID OVERDOSE
Maximizing safety is also one of FIRODYL®'s goals.
By being able to divide the tablet into 4 equal parts, the administered dose will always be as close as possible to the recommended dose (5mg / kg).
4. ADAPTED CONCENTRATIONS
FIRODYL® is marketed in concentrations (62.5mg and 250mg) and in packs of 96 tablets that allow adjusting the doses and optimizing the cost of the treatment.
In long-term treatments and especially in large breeds, cost can become a factor that affects adherence to treatment.
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